- ￥3000 - 3999
- Abbiotec
- 美国
- 253921
- 2025年12月11日
- E, WB
- Rabbit
- H, M, R
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- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human ASAH2.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 宿主：
Rabbit
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
ASAH2
- 抗体英文名：
ASAH2 Antibody
- 抗体名：
ASAH2 Antibody
- 规格：
0.1 mg
ASAH2 Antibody产品详细介绍：
| 产品名称： | ASAH2 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253921 |
| 规格： | 0.1 mg |
| 产品描述： | Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids. These ceramidases are classified according to the pH range that supports their optimal activity. ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5. ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger. ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart. Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human ASAH2. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名： | ASAH2; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; HNAC1 |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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ASAH2 Antibody
￥3000 - 3999
