- ￥3000 - 3999
- Abbiotec
- 美国
- 253500
- 2025年07月12日
- E
- Rabbit
- Bact
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of the Anthrax protective antigen protein.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
Bact
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of the Anthrax protective antigen protein.
- 目录编号：
253500
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E
- 浓度：
见详细说明信息
- 靶点：
Anthrax Protective Antigen
- 抗体英文名：
Anthrax Protective Antigen Antibody
- 抗体名：
Anthrax Protective Antigen Antibody
- 规格：
0.1 mg
Anthrax Protective Antigen Antibody产品详细介绍：
| 产品名称： | Anthrax Protective Antigen Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253500 |
| 规格： | 0.1 mg |
| 产品描述： | Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of the Anthrax protective antigen protein. |
| 适用物种： | Bact |
| 应用范围： | E |
| 应用说明： | E: 1:500-1:1,000 |
| 别名： | Anthrax Protective Antigen ; Anthrax PA |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
Anthrax toxin is a three-part toxin secreted by Bacillus anthracis , consisting of protective antigen (PrAg), edema factor (EF), and lethal factor (LF). To intoxicate host mammalian cells, PrAg, the cell-binding moiety of the toxin, binds
抗原抗体反应 antigen－antibody reaction
基于抗原同抗体的特异性结合产生的现象总称。实际的结合取决于抗原的抗原决定簇和抗体的抗原结合部位（结合簇）（antigen combining site）之间的特殊结合。在生物体内发生的抗原抗体反应（免疫、过敏反应、溶血等）多数也可在试管内再现，利用这一点发展了抗原或抗体的定性及定量的试验方法。像酶、毒素、病毒之类具有生物学活性的抗原，一与抗体（中和抗体）结合，其活性便消失或减弱（中和反应， neutralizing reaction）。带有可溶性的复数抗原决定簇的抗原分子，与抗体互相
Crystallographic Studies of Antigen-Antibody Interactions
X-ray crystallography provides a powerful tool for the study of antigen- antibody interactions. Information provided by crystallographic studies of antigen-antibody complexes includes the topological description of intermolecular contacts
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