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- 2025年07月16日
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- 技术资料
- 抗体英文名：
cFMS Receptor Inhibitor IV
- 规格：
5MG
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文献和实验Receptor Tyrosine Kinase Inhibitor Profiling Using Bead-Based Multiplex Sandwich Immunoassays
Receptor tyrosine kinases (RTK) are important targets in drug discovery processes. Studying the phosphorylation pattern of RTKs enables the determination of their activation and inactivation states. Multiplex bead-based sandwich immunoassays
with FGF signaling by treating embryos with SU5402 (Calbiochem), a FGF receptor inhibitor. We observed craniofacial deformities and delayed maturation in embryos treated with SU5402. this indicates that FGF signaling is required for cranifacial formation
Methods to Assay Inhibitors of DNA Gyrase and Topoisomerase IV Activities
on DNA supercoiling by S. pneumoniae gyrase, DNA decatenation by S. pneumoniae topo IV, and DNA cleavage by both enzymes. These approaches provide mechanistic insight on inhibitor action and allow identification of dual gyrase/topo IV targeting agents
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