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文献和实验Synthesis of Monensin Derivatives and Their Effect on the Activity of Ricin A-Chain Immunotoxins
Cell-specific cytotoxic heteroconjugates are made by linking bacterial toxins (e.g., diphtheria toxin, Pseudomonas exotoxin A) or plant toxins (e.g., ricin, abrin) to monoclonal antibody (MAb)/ligands that bind target antigens or receptors
The production of monoclonal antibody by hybridoma
The production of monoclonal antibody by hybridoma fusion: Immortalization of sensitized B lymphocytes from immune mice.
Antibodies to native B-DNA are common in systemic lupus erythematosus (SLE), and their measurement serves as a diagnostic and prognostic marker of the disease (1 ). Autoreactive antibodies are also found in the sera of normal individuals
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