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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 英文名：
NF-κB (p50) (human recombinant)
- 库存：
1
- 供应商：
甄准生物
- 保存条件：
-80.0
- 规格：
10 µg
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- 作者
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文献和实验Activation of Nuclear Factor-B (NF-B) in Mononuclear Cells (MNC)
is a heterodimer, which usually consists of two proteins, a p65 (relA) subunit and a p50 subunit. Other subunits (rel, relB, v-rel, and p52) can also bind to the activated NF-κB and thus can activate different sets of genes.
The nuclear factor-kappa B (NFκB) family of transcription factors has emerged as a signaling pathway that figures prominently in a cell’s initial response to a plethora of inflammatory stimuli. Modified lipids, oxidative stress, bacterial
that each of the five NF-κB subunits may have a specific function in controlling the expression of inflammatory mediators in immune cells. Identifying the role for each NF-κB subunit in primary human immune cells will allow a more targeted approach to inhibiting NF-κB
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