1) Cat. No.: TRC-V678500; 2) Chemical Name: Voclosporin; 3) CAS No.: 515814-01-4; 4) Mol. Formula: C63H111N11O12; 5) Mol. Weight: 1214.62; 6) Packing Size: 2.5mg / 25mg; 7) Appearence: ; 8) Application Notes: A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant. ; 9) Synonym: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A; ISATX 247; R 1524; trans-ISA 247; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Aspeslet, L., et al.: Transplant Proc., 33, 1048 (2001), Cho, M., et al.: Arthritis Rheum., 46, 1202 (2002), Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2004),