FIIN-1

1) Cat. No.: TRC-F336500; 2) Chemical Name: FIIN-1; 3) CAS No.: 1256152-35-8; 4) Mol. Formula: C32H39Cl2N7O4; 5) Mol. Weight: 656.6; 6) Packing Size: 10mg / 100mg; 7) Appearence: ; 8) Application Notes: FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1.The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.; 9) Synonym: N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; FGFR Irreversible Inhibitor 1; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Zhou, W. et al.: Chem. Biol., 17, 285 (2010);