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- 英文名:
rac N-Deformyl Formoterol Fumarate
- 库存:
1
- 供应商:
甄准生物
- 规格:
10mg / 100mg
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文献和实验Identification and Functional Reconstitution of Effector Proteins for the GTPases Rac and CDC42HS
Aldrich Syndrome Protein (WASP) ( 7 , 8 ). Rho was recently shown to interact with several protein kinases related to protein kinase N ( 9 , 10 ). Fig. 1. Cycling between the “on” and “off” states of Ras-like GTPases is regulated by GEFs
Assessment of Rho GTPase Signaling During Neurite Outgrowth
Rho GTPases are key regulators of the cytoskeleton during the process of neurite outgrowth. Based on overexpression of dominant-positive and negative Rho GTPase constructs, the classic view is that Rac1 and Cdc42 are important for neurite
Ras 信号通路 很多生长因子如EGF、PDGF、FGF等激活受体酪氨酸激酶后,通过中介分子可活化由原癌基因FaS编码的Ras蛋白 ,后者能进一步催化其底物蛋白的酪氨酸磷酸化反应,并引发蛋白磷酸化的级联反应,最终导致细胞的增殖效应。由于Ras蛋白为多种生长因子信号转导过程所共有,故把此信号转导途径称为Ras通路。 Ras蛋白是癌基因las的编码产物,人类有3种ras基因,即H―FaS、K―las和N―Fas,分布于不同染色体上,能编码蛋白质P21。所有的Ras―P21均有结合鸟
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