Combretastatin A4 Phosphate Di

1) Cat. No.: TRC-C643025; 2) Chemical Name: Combretastatin A4 Phosphate Disodium Salt; 3) CAS No.: 168555-66-6; 4) Mol. Formula: C18H19Na2O8P; 5) Mol. Weight: 440.29; 6) Packing Size: 5mg / 50mg; 7) Appearence: White Solid; 8) Application Notes: Phosphorylated Combretastatin, a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.; 9) Synonym: 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 1-(Dihydrogen phosphate) Sodium Salt; CA 4P; ; 10) Solubility: Methanol; 11) Storage condition: Refrigerator; 12) References: Hamel, E., et al.: Biochem. Pharmacol., 32, 3863 (1983), Chaplin, D.J., et al.: Br. J. Cancer, 74, S86, (1996)