LD Biopharma Recombinant Human PRMT3 Protein [HRP-0504]产品图
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LD Biopharma Recombinant Human

PRMT3 Protein [HRP-0504]
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  • $300
  • LD Biopharma
  • 美国
  • HRP-0504
  • 2026年10月18日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件:

      In Liquid. Keep at -20°C for long term storage. Product is stable at 4 °C for at least 30 days.

    • 英文名:

      Recombinant Human PRMT3 Protein

    • 规格:

      50 µg / Vial

    Recombinant Human PRMT3 Protein,品牌LD Biopharma,货号HRP-0504,规格50 µg / Vial。 基因符号:PRMT3 ( HRMT1L3 ) 登录号:NP_005779.1 物种:Human 质量控制:1. Purity: > 90% by SDS-PAGE. 制剂组成:0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. 英文说明:Protein post-translational modification, such as arginine methylation not only plays a major role in epigenomic regulation, such as histone and transcription factor modification, but also regulates many RNA binding proteins functions. There are at least eight type I protein arginine N-methyltransferases (PRMTs) were identified from human genome. Human PRMT3 (protein arginine N-methyltransferase 3), as a member of PRMT protein family, catalyze the formation of asymmetric N(G), N(G)-dimethylarginine (ADMA) residues in proteins. Full-length recombinant human PRMT3 cDNA (465aa, derived from BC001878, isoform 1) was constructed with codon optimization with a small T7-His-TEV cleavage site Tag (29aa) fusion at its N-terminal. This protein was expressed in E. coli as inclusion bodies, refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified. 应用信息:1. May be used for in vitro human PRMT3 functional regulations using protein mediated intracellular dilivery study. 2. May be used for specific substrate protein for kinase and ubiquitin related enzyme functional screening assays. 3. May be used as antigen for specific antibody production. 本品仅供科研使用。实际构建、质量控制、保存及使用要求请以批次文件为准;网站目录不代表当前库存或实际供货承诺。

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    图标文献和实验
    该产品被引用文献
    Kolbel,K., et al., Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively. J. Biol. Chem. 284 (13), 8274-8282 (2009) Tavanez,J.P., et al., Hsp70 chaperones and type I PRMTs are sequestered at intranuclear inclusions caused by polyalanine expansions in PABPN1. PLoS ONE 4 (7), E6418 (2009) Singh,V., et al., DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo. Oncogene 23 (47), 7761-7771 (2004)
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    文献支持
    LD Biopharma Recombinant Human PRMT3 Protein [HRP-0504]
    $300