LD Biopharma Recombinant Human

Recombinant Human ANKRD1 Protein，品牌LD Biopharma，货号HRP-1302，规格50 µg / Vial。 基因符号：ANKRD1 (ALRP; bA320F15.2; C-193; CARP; CVARP) 登录号：NP_055206 物种：Human 质量控制：Purity: > 90% by SDS-PAGE. 制剂组成：0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Sucrose. 英文说明：The protein encoded by human ankyrin repeat domain-containing protein 1 (ANKRD1) gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. Recent data also indicated that induction of ANKRD1 seems to be corrected with apoptotic cell death in hepatoma cells. Full-length human ANKRD1 cDNA (2–319 aa) was constructed with codon optimization and expressed with a small T7-His-TEV cleavage site Tag (31aa) fusion at its N-terminal. This protein is expressed in E.coli as inclusion bodies. The final product was refolded using our unique “temperature shift inclusion body refolding” technology and chromatographically purified. 应用信息：1. May be used for in vitro ANKRD1 mediated DNA transcription regulation for endothelial cell activation study with “ProFectin” based intracellular delivery of this protein. 2. May be used for ANKRD1 protein – protein interaction assay. 3. Potential diagnostic biomarker protein. 4. May be used for specific antibody production. 本品仅供科研使用。实际构建、质量控制、保存及使用要求请以批次文件为准；网站目录不代表当前库存或实际供货承诺。