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- 技术资料
- 英文名:
Recombinant Biotinylated Cynomolgus NCR₃LG₁(B7-H6) Protein,His-Avi Tag
- 保存条件:
-85 ~ -65℃保存,收到货之日起,6个月有效期。避免反复冻融,建议等分分装为一次实验使用量,分装后,-80℃冻存。
- 规格:
25 μg(94052ES25)/200 μg(94052ES70)
| 规格: | 25 μg(94052ES25) | 产品价格: | ¥3795 |
|---|---|---|---|
| 规格: | 200 μg(94052ES70) | 产品价格: | ¥14695 |
产品描述:
B7-H6 protein is a co-stimulatory molecule that belongs to the B7 family. It is encoded by the NCR₃LG₁ gene and is a protein associated with the human immune system. B7-H6 protein was initially discovered in human tumor cells and later detected in other tissues and cells.
B7-H6 protein regulates the activity of NK cells (natural killer cells) by binding to the NKP30 receptor on the surface of NK cells. NK cells are an important type of lymphocyte with the ability to directly kill tumor cells and infected cells, making them crucial members of the immune system.
Research indicates that B7-H6 protein plays a significant role in regulating the activity of NK cells, promoting cytotoxicity, and modulating immune responses. Additionally, the expression of B7-H6 protein is associated with tumor development and immune evasion, making it a potential target for immunotherapy.
产品属性:
| 产品别称 | B7-H6,NCR₃LG₁, B₇H₆,B7 Homolog 6 |
| 种属 | Cynomolgus |
| 表达序列 | Asp 25 - Asp 259 |
| Accession | A₀A₂K₆ALK₃ |
| 标签 | C-His-Avi Tag |
| 表达系统 | HEK293 |
| 分子量 | The protein has a predicted MW of 28.4 kDa |
| 纯度 | > 95% as determined by SDS-PAGE |
| 内毒素 | < 1.0 EU per μg by the LAL method. |
| 制剂 | Supplied as a 0.2 μm filtered solution of PBS, pH7.4. |
| 外观 | Liquid |
| 生物活性 | ELISA: Biotinylated Cynomolgus NCR₃LG₁(B7-H6) Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-B7-H6 hIgG1 Antibody were added. |
产品特色:
高纯度、高活性、低内毒素、高批间一致性
应用案例:
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Biotinylated Cynomolgus NCR₃LG₁(B7-H6) Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-B7-H6 hIgG1 Antibody were added.
储存条件:
-85 ~ -65℃保存,收到货之日起,6个月有效期。避免反复冻融,建议等分分装为一次实验使用量,分装后,-80℃冻存。
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