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- 库存:
42
- 供应商:
广州市左克生物
- 规格:
100 μg
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产品简介:
货号:Z05326-100
产品名称:Galectin 9/LGALS9, His, Human
产品规格:100 μg
产品介绍文本:Galectin-9 is a secreted carbohydrate-binding protein with two lectin domains connected by a linker region.Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine , which can be bound to proteins by either N-linked or O-linked...
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| Target Background | Galectin-9 is a secreted carbohydrate-binding protein with two lectin domains connected by a linker region.Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine , which can be bound to proteins by either N-linked or O-linked glycosylation. |
| Synonyms | Ecalectin; GAL9; gal-9; Galectin9; Galectin-9; HUAT; LGALS9; LGALS9A; MGC117375; MGC125973; MGC125974 |
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文献和实验Galectin-3 Binding and Metastasis
in transformed and metastatic cell lines (Raz and Lotan Cancer Metastasis Rev 6: 433–452, 1987; Raz et al. Int J Cancer 46: 871–877, 1990). Moreover, in many human carcinomas, an increased expression of galectin-3 correlates with progressive tumor stages (Lotan
素-8(Galectin-8),通过激活STAT3、抑制NF-κB通路,促进M-MDSC扩增,构建免疫抑制微环境,助长肿瘤进展。这些相互作用凸显LILRB4在免疫调节与肿瘤发展中的关键地位。 LILRB4的免疫调节机制 LILRB4通过多种机制抑制免疫细胞活化,促进免疫耐受。在T细胞中,LILRB4与PD-1、LAG-3等共表达,诱导T细胞耗竭,并促进调节性T细胞(Treg)分化,抑制效应T细胞应答;其可溶性形式可导致CD4+ T细胞无反应性,减少IL-1α、IL-6等促炎因子释放。在NK细胞中,LILRB4与纤
Human mesenchymal stem cells (hMSCs) are multipotent stem cells that can differentiate into a variety of cell types in vitro including osteoblasts, adipocytes, and chondrocytes. Here we apply a metabolic labeling approach to characterize
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