IL-4/BSF-1 (C-6His), Human, Re

IL-4/BSF-1 (C-6His), Human, RecombinantIL-4/BSF-1 (C-6His), Human, RecombinantInterleukin-4;IL-4;B-Cell Stimulatory Factor 1;BSF-1;Binetrakin;Lymphocyte Stimulatory Factor 1;Pitrakinra;IL4

IL-4/BSF-1 (C-6His), Human, Recombinant PCK032

背景介绍：Interleukin-4 (IL-4) is a pleiotropic Cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their Cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

产品形态	粉末
产品规格	1mg、10μg、50μg、500μg
别名	Interleukin-4;IL-4;B-Cell Stimulatory Factor 1;BSF-1;Binetrakin;Lymphocyte Stimulatory Factor 1;Pitrakinra;IL4
物种	人
表达宿主	Human Cells
序列信息	His25-Ser153
检索号	P05112
分子量	16 kDa
表观分子量	18 kDa
标签	C-6His
生物活性	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL.
纯度	> 95% as determined by reducing SDS-PAGE.
内毒素	< 0.1 EU/μg
储存条件	Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件	Ambient temperature or ice pack.
有效期	12个月
制剂	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
体系描述	GMP生产和质量体系 公司符合cGMP的要求，已通过NMPA的第一类医疗器械生产备案，且通过ISO 13485和ISO 9001标准认证。公司生产的IL-4/BSF-1 (C-6His), Human, Recombinant符合ISO 9001的cGMP标准。

产品问答FAQs：

Q：收到细胞因子产品用什么溶剂复融？

A：1、细胞因子产品大部分为冻干形式发货，少部分液体形式发货； 2、冻干粉状态的因子产品需指定溶剂复溶，请参考产品手册【复融】方法，按照要求使用对应溶剂溶解，大部分因子为无菌水复融，少部分需要无菌水以外的特殊溶剂溶解的产品则随货会赠送相应的复融试剂；冻干粉溶解后如您需要进一步稀释分装，需使用含载体蛋白(如0.1% BSA，10%FBS，5%HSA 或 5% 海藻糖)的溶液进一步稀释后分装冷冻保存。 3、液体形式因子产品不需要复溶，具体浓度详见产品标签，按照实验需要用含载体蛋白(如0.1% BSA，10%FBS，5%HSA 或 5% 海藻糖)的溶液进一步稀释后分装冷冻保存即可；

Q：细胞因子离心前需要放置室温吗？

A：不用提前放置室温.

Q：细胞因子加无菌水溶解后需要再次离心吗？

A：加了无菌水后，如果没有挂壁现象是不用离心的，如果您放置了一段时间，再次使用时是可以使用离心机离心的

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IL-4/BSF-1 (C-6His), Human, Recombinant Ambient temperature or ice pack. Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. 12个月