MSLN Antibody / Mesothelin 抗体,orb2644780,Biorbyt产品图

MSLN Antibody / Mesothelin 抗体,

orb2644780,Biorbyt
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  • ¥8775
  • Biorbyt已认证
  • orb2644780
  • 英国
  • 2026年08月07日
  • IHC-P, WB
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 抗体名:

      MSLN Antibody / Mesothelin 抗体

    • 抗体英文名:

      MSLN Antibody / Mesothelin

    • 应用范围:

      IHC-P, WB

    • 宿主:

      Mouse

    • 适应物种:

      Human

    • 保质期:

      12 months from date of receipt.

    • 抗原来源:

      详询

    • 目录编号:

      orb2644780

    • 级别:

      科研

    • 库存:

      99

    • 供应商:

      Biorbyt

    • 标记物:

      Unconjugated

    • 克隆性:

      Monoclonal

    • 保存条件:

      详询

    • 亚型:

      Mouse IgG1, kappa

    • 免疫原:

      详询

    • 规格:

      100 ug

    类别: Antibodies

    产品子类型: Primary Antibody

    描述: Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

    克隆号: MSLN/3387

    应用稀释比例: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT,Western blot: 2-4ug/ml

    应用说明: Optimal dilution of the MSLN antibody should be determined by the researcher.

    免疫原: A portion of amino acids 273-407 from the human protein was used as the immunogen for the MSLN antibody.

    防腐剂: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

    纯化方法: Protein G affinity chromatography

    UniProt ID: Q13421

    保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    备注: For research use only.

    产品细节图片1
    IHC staining of FFPE human mesothelioma with MSLN antibody. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

    产品细节图片2
    IHC staining of FFPE human mesothelioma with MSLN antibody. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

    产品细节图片3
    Analysis of HuProt (TM) microarray containing more than 19000 full-length human proteins using MSLN antibody. These results demonstrate the foremost specificity of the MSLN/3387 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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