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- Elabscience
- PDEH100760
- 湖北武汉
- 2026年09月11日
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- 文献和实验
- 技术资料
- 库存：
999
- 保质期：
12个月
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 保存条件：
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- 规格：
100 μg/20 μg
| 规格： | 100 μg | 产品价格： | ￥3600.00 |
|---|---|---|---|
| 规格： | 20 μg | 产品价格： | ￥1200.00 |
产品简称：Fyn
英文名称：Recombinant Human Fyn Protein(His Tag)
背景：Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin). Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT. Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage. Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm by phosphorylating several slit diaphragm components including NPHS1, KIRREL1 and TRPC6. Plays a role in neural processes by phosphorylating DPYSL2, ARHGAP32 and SNCA. Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation. Phosphorylates PTK2B/PYK2 in response to T-cell receptor activation. Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts.
运输条件：This product is provided as lyophilized powder which is shipped with ice packs.
实验图：
Elabscience供应Recombinant Human Fyn protein(His Tag)，这些蛋白质中的大多数纯度≥95%，内毒素水平≤1.0EU/μg，并且已经过活性验证，助力您科学实验。
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