- ￥966 - 2240
- Elabscience
- PKSH032417
- 湖北武汉
- 2026年09月11日
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- 文献和实验
- 技术资料
- 库存：
999
- 保质期：
12个月
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 保存条件：
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- 规格：
10 μg/50 μg
| 规格： | 10 μg | 产品价格： | ￥966.00 |
|---|---|---|---|
| 规格： | 50 μg | 产品价格： | ￥2240.00 |
产品简称：CD32a
英文名称：Recombinant Human CD32a/FCGR2A Protein (His Tag)
背景：Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (CD32), and FcγRIII (CD16), which generate multiple isoforms, are recognized. The activating- type receptor either has or associates non-covalently with an accessory subunit that has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. FcγRI binds IgG with high affinity and functions during early immune responses, whereas FcγRII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Three genes for human FcγRII (A, B, and C) and one for mouse (FcγRIIB), encoding type I transmembrane proteins with ITAM motifs (FcγRII A and C) or ITIM motifs (FcγRIIB) in their cytoplasmic domains, have been identified. Human CD32, also known as Low affinity immunoglobulin γ Fc region receptor II-a, FcγRII A or FCGR2A Protein, is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Associated with an ITAM-bearing adapter subunit, FcRγ, CD32a delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation, and cytokine production.
运输条件：This product is provided as lyophilized powder which is shipped with ice packs.
实验图：
Elabscience供应Recombinant Human CD32a/FCGR2A Protein (His Tag)，这些蛋白质中的大多数纯度≥95%，内毒素水平≤1.0EU/μg，并且已经过活性验证，助力您科学实验。
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