重组人生长停滞和DNA损伤可诱导蛋白α(GADD45A)

产品英文名称：
Recombinant Human Growth Arrest and DNA-Damage-Inducible Alpha

英文简称:
GADD45A

中文名称:
重组人生长停滞和DNA损伤可诱导蛋白α

背景资料:
Growth arrest and DNA Damage-Inducible Protein （GADD45A） binds both Cdks and PCNA. GADD45A is involved in DNA replication and repair. GADD45A stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A may serve as a link betwGADD45A produced in E.Coli is a single， non-glycosylated polypeptide chain containing 173 amino acids （1-165 a.a.） and having a molecular mass of 19.4kDa. GADD45A is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques.n p53-dependent cell cycle checkpoint and DNA repair. The GADD45A gene belongs to a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45A binds to proliferating cell nuclear antigen.

产品描述:
GADD45A produced in E.Coli is a single， non-glycosylated polypeptide chain containing 173 amino acids （1-165 a.a.） and having a molecular mass of 19.4kDa. GADD45A is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

溶解建议:
Sterile filtered colorless solution. The GADD45A protein solution contains 20mM Tris-HCl buffer （pH8.0）， 10% glycerol and 0.1M NaCl.

保存建议：
Store at 4℃ if entire vial will be used within 2-4 weeks. Store， frozen at -20℃ for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles.
应用领域：
重组人生长停滞和DNA损伤可诱导蛋白α产品可广泛应用于免疫检测研究、抗体开发、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。

关键词：
重组人生长停滞和DNA损伤可诱导蛋白α、Recombinant Human Growth Arrest and DNA-Damage-Inducible Alpha、GADD45A、重组蛋白、多肽、抗原、原核表达、His标签

其他简介：

 
CMBIO