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文献和实验The production of uniform protein-binding biofunctional fluorescent spherical silica core–shell nanoparticles by a modified St�ber method is described. Fluorescent particle cores with diameters of 100 nm are synthesized in a two-step reaction
system. 3. SIFs and SACS Trisodium citrate was supplied by Spectrum. Silver nitrate and glucose were from Sigma-Aldrich. Microscope slides were coated by EMF Corp. (Ithaca, NY). A 52-nm thick layer of silver was deposited on the slide
to ensure collection of the sample. Resin binding A very popular method is to bind the DNA to silica particles by using commercially available binding resins, diatomaceous earth or glass fibers. This method was previously described in Methods
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