Nectin-4(enfortumab)参照抗体产品图

Nectin-4(enfortumab)参照抗体

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  • ¥800
  • DIMA BIOTECH/缔码生物
  • 武汉
  • BME100088
  • 2026年07月10日
  • ELISA; Flow Cyt
  • Homo sapiens
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原:

      inquire

    • 亚型:

      Human IgG1 - kappa

    • 形态:

      Powder

    • 保存条件:

      Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    • 克隆性:

      Monoclonal

    • 标记物:

      Unconjugated

    • 适应物种:

      Human

    • 级别:

      Research use only

    • 库存:

      In Stock

    • 供应商:

      缔码生物(武汉)科技有限公司

    • 宿主:

      Homo sapiens

    • 应用范围:

      ELISA; Flow Cyt

    • 浓度:

      详见COA

    • 靶点:

      Nectin-4

    • 抗体英文名:

      Anti-Nectin-4(enfortumab biosimilar) mAb

    • 抗体名:

      Anti-Nectin-4(enfortumab biosimilar) mAb

    • 规格:

      50μg

    产品类型 Biosimilar reference antibodies
    靶点 Nectin-4
    Uniprot ID Q96NY8
    背景 Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. Our unconjugated biosimilar monoclonal antibodies (mAbs) are based on the sequences outlined in relevant patents or scientific publications. These antibodies are in their native, unconjugated form, meaning they do not contain any payload or therapeutic agent attached. They are designed for use in research and development, and their performance has been tested as standalone molecules through comprehensive QC tests.
    通用名 enfortumab, Unconjugated mAb
    货期 In Stock
    产品英文名称 Anti-Nectin-4(enfortumab biosimilar) mAb
    内毒素 Less than 1.0 EU/μg by the LAL method. For <1 EU/mg requirements, please contact us for customization.
    保质期 12 months from date of dispatch
    无菌性 Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use.
    储存与运输 Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    别名 EDSS1;LNIR;nectin-4;PRR4;PVRL4
    应用 ELISA; Flow Cyt
    有无偶联 Unconjugated
    组分 Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
    宿主种属 Homo sapiens
    IgG亚型 Human IgG1 - kappa
    反应种属 Human
    推荐稀释比 ELISA 1:5000-10000; Flow Cyt 1:100
    应用范围 Research use only
    BME100088-BM230-Anti-Nectin-4-Neutralizing-antibody-ELISA-Fig1.jpg
    Figure 1. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human NECTIN-4 Protein, His Tag PME100874 can bind Anti-Nectin-4 Neutralizing antibody ( BME100088) in a linear range of 0.61–39.06 ng/mL.
    BME100088-BM230-Anti-Nectin-4-FACS-Fig2.jpg
    Figure 2. Flow cytometry analysis with 1 μg/mL Anti-Nectin-4 (enfortumab biosimilar) mAb (BME100088) on HEK293 cells transfected with Human Nectin-4 protein (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).
    bme100088-nectin-4-fc2.jpg
    Figure 3. Flow cytometry analysis of antigen binding of anti-human Nectin-4 mAb(BME100088). (A) BME100088 does not bind to 293T cells that do not express Nectin-4. (B) A clear peak shift of BME100088 was seen compared to the control when incubated with Nectin-4-expressing A431 cells, indicating strong binding of BME100088 to Nectin-4. Antibodies were incubated at 2 μg/mL.

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