- ￥800
- DIMA BIOTECH/缔码生物
- 武汉
- BME100054
- 2026年07月10日
- ELISA; Flow Cyt
- Chimeric
- Human
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- 文献和实验
- 技术资料
- 免疫原：
inquire
- 亚型：
Human IgG4 - Kappa
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 级别：
Research use only
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Chimeric
- 应用范围：
ELISA; Flow Cyt
- 浓度：
详见COA
- 靶点：
BTLA
- 抗体英文名：
Anti-BTLA (icatolimab biosimilar)mAb
- 抗体名：
Anti-BTLA (icatolimab biosimilar)mAb
- 规格：
50μg
| 产品类型 | Biosimilar reference antibodies |
|---|---|
| 靶点 | BTLA |
| Uniprot ID | Q7Z6A9 |
| 背景 | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| 通用名 | JS004 |
| 货期 | In Stock |
| 产品英文名称 | Anti-BTLA (icatolimab biosimilar)mAb |
| 内毒素 | Less than 1.0 EU/μg by the LAL method. For <1 EU/mg requirements, please contact us for customization. |
| 保质期 | 12 months from date of dispatch |
| 无菌性 | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 别名 | BTLA;CD272 |
| 应用 | ELISA; Flow Cyt |
| 有无偶联 | Unconjugated |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 宿主种属 | Chimeric |
| IgG亚型 | Human IgG4 - Kappa |
| 反应种属 | Human |
| 推荐稀释比 | ELISA 1:5000-10000; Flow Cyt 1:100 |
| 应用范围 | Research use only |
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human BTLA , His tagged protein ([getskuurl sku="PME100524"]) can bind Anti-BTLA Neutralizing antibody (BME100054) in a linear range of 1-100 ng/ml.
Figure 2. Flow cytometry analysis with Anti-BTLA mAb 1 μg/ml (icatolimab) on HEK293 cells transfected with human BTLA (Blue histogram)or HEK293 transfected with irrelevant protein (Red histogram) .风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验细胞形成以及浆细胞抗体的产生。 ②PD-1(CD279)，与CTLA-4有24％同源性，胞质区有1个ITIM。PD-1在T细胞呈活化后诱导性表达，其配体为B7―H1／PD-L1(CD274)和B7-DC／PD-L2(CD273)，P1)-I与相应配体结合后，胞质区ITIM中酪氨酸发生磷酸化，募集SHP-2，从而抑制T细胞的增殖，抑制IL-2、IL-10和IFN-7等细胞因子的产生，并对B细胞的增殖、分化与Ig分泌及Ig类别转换有抑制作用。 ③BTLA、CD272结构上与CTLA
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