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- 技术资料
- CAS号：
1903742-34-6
- 规格：
1mLx10mM(inDMSO)/1mg/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥2664.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥896.0 |
| 规格： | 5mg | 产品价格： | ￥2144.0 |
| 规格： | 10mg | 产品价格： | ￥3224.0 |
| 规格： | 25mg | 产品价格： | ￥4784.0 |
| 规格： | 50mg | 产品价格： | ￥6384.0 |
| 规格： | 100mg | 产品价格： | ￥8560.0 |
| 规格： | 200mg | 产品价格： | ￥11440.0 |
Product Introduction
Bioactivity
| 名称 | Complement factor D-IN-2 |
| 描述 | Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D. |
| 体外活性 | Complement factor D-IN-2 作用于因子D，从而在替代性补体途径的早期和重要节点抑制补体级联反应[1]。 |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 70 mg/mL (121.86 mM), Sonication is recommended. |
| 关键字 | Inhibitor | inhibit | factor D | factor | diseases | ComplementSystem | Complement System | Complement factor D-IN-2 | Complement factor DIN2 | Complement factor D IN 2 | complement | autoimmune |
| 相关产品 | Cyclosporin A | Dexamethasone acetate | CP-289 | Dextran sulfate sodium salt (MW 5000) | Dexamethasone | BCX 1470 hydrochloride | Iptacopan hydrochloride | ADH-503 | Iptacopan | 3-Phenoxybenzaldehyde | EG01377 2HCl | Avacopan |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Immunology/Inflammation Compound Library |
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文献和实验Purification, Quantification, and Functional Analysis of Complement Factor H
Complement Factor H (FH) is an abundant, non-enzymic plasma/serum glycoprotein, which has a major role in regulating activation of the complement system. It can be purified from human plasma/serum by affinity chromatography, using
Functional Assays for Complement Regulators
As described in Chapter 1, the complement system comprises a battery of at least 20 components capable of immediate response to a foreign organism or cell, resulting in lysis or opsonization and phagocytosis. Uncontroled complement activation
Factor H-related proteins (CFHRs) are plasma glycoproteins related in structure and antigenicity to each other and to the complement inhibitory protein factor H. Such proteins are found in most mammals but their number and domain composition
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