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- 2026年07月07日
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5μg/10μg/20μg/50μg
| 规格： | 5μg | 产品价格： | ￥248.0 |
|---|---|---|---|
| 规格： | 10μg | 产品价格： | ￥260.0 |
| 规格： | 20μg | 产品价格： | ￥413.0 |
| 规格： | 50μg | 产品价格： | ￥937.0 |
Product Introduction
Bioactivity
| 名称 | CDK5 Protein, Human, Recombinant (GST) |
| 描述 | Cell division protein kinase 5, also known as Cyclin-dependent kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit and CDK5, is a cytoplasm protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2 / CDKX subfamily. Cyclin-dependent kinases (Cdks) are a family of proline-directed Ser/Thr kinases known for their role in the control of cell cycle progression. In 1992, this family was joined by CDK5, which is an atypical member in that it uses its own activators and is multifunctional, playing important regulatory roles in multiple cellular functions. CDK5, unlike other Cdks, is not regulated by cyclins, and its activity is primarily detected in postmitotic neurons in developing and adult nervous systems. CDK5 is activated by association with a neuron-specific activator, p35 or its isoform p39. CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. CDK5 can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. It also interacts with p35 which activates the kinase. CDK5 plays important roles in various neuronal activities, including neuronal migration, synaptic activity, and neuronal cell death. |
| 存储条件 | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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文献和实验/thread/339070 GST融合蛋白纯化合作 http://www.dxy.cn/bbs/thread/591287 目的蛋白不溶于水是否可以做GST融合表达？ http://www.dxy.cn/bbs/thread/164507 讨论原核表达条件优化者请进！ http://www.dxy.cn/bbs/thread/252999 请问：重组蛋白如何大规模纯化？ http://www.dxy.cn/bbs/thread/215536 求救：我的蛋白质在降解
义翘神州日前曾邀请杨嘉慧博士进行了一场题为「获得高品质重组蛋白实验方案以及经典案例分析」技术公开课，课后收到了很多专业的提问，现将相关的问答简单列举一些，希望能够帮助更多的人获得高质量的重组蛋白。1. 是不是质粒片段越大转染效率越低?解答：一般情况是这样的，质粒片段越大，转染效率越低，但这也与表达宿主有关，不能一概而论。所以有时在进行表达载体优化时，会将质粒的片段或非重要功能区的一些片段进行删减，可以获得较好的转染效率。2.HEK293 瞬转表达重组蛋白相对于 CHO，哪个更有优势？解答
摘要 Groundbreaking work demonstrated that ectopic expression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc, could reprogram murine somatic cells to induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), and human
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