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5μg/10μg/20μg/50μg
| 规格： | 5μg | 产品价格： | ￥271.0 |
|---|---|---|---|
| 规格： | 10μg | 产品价格： | ￥409.0 |
| 规格： | 20μg | 产品价格： | ￥684.0 |
| 规格： | 50μg | 产品价格： | ￥1563.0 |
Product Introduction
Bioactivity
| 名称 | RSK4 Protein, Human, Recombinant (GST) |
| 描述 | Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA6 contains one AGC-kinase C-terminal domain and two protein kinase domains. RPS6KA6 forms a complex with either ERK1 or ERK2 in quiescent cells. RPS6KA6 shows a high level of homology to three isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RPS6KA6 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RPS6KA6 plays a role in normal neuronal development. Further mutation analyses in males with X-linked mental retardation must prove that the gene of RPS6KA6 is indeed a novel MRX gene. RPS6KA6 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. RPS6KA6 is activated by multiple phosphorylations on threonine and serine residues. |
| 存储条件 | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
| 关键字 | RSK-4 | RSK 4 |
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文献和实验/thread/339070 GST融合蛋白纯化合作 http://www.dxy.cn/bbs/thread/591287 目的蛋白不溶于水是否可以做GST融合表达？ http://www.dxy.cn/bbs/thread/164507 讨论原核表达条件优化者请进！ http://www.dxy.cn/bbs/thread/252999 请问：重组蛋白如何大规模纯化？ http://www.dxy.cn/bbs/thread/215536 求救：我的蛋白质在降解
义翘神州日前曾邀请杨嘉慧博士进行了一场题为「获得高品质重组蛋白实验方案以及经典案例分析」技术公开课，课后收到了很多专业的提问，现将相关的问答简单列举一些，希望能够帮助更多的人获得高质量的重组蛋白。1. 是不是质粒片段越大转染效率越低?解答：一般情况是这样的，质粒片段越大，转染效率越低，但这也与表达宿主有关，不能一概而论。所以有时在进行表达载体优化时，会将质粒的片段或非重要功能区的一些片段进行删减，可以获得较好的转染效率。2.HEK293 瞬转表达重组蛋白相对于 CHO，哪个更有优势？解答
摘要 Groundbreaking work demonstrated that ectopic expression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc, could reprogram murine somatic cells to induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), and human
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