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- CAS号:
1029714-89-3
- 规格:
1mg/5mg/10mg/25mg/50mg/100mg
| 规格: | 1mg | 产品价格: | ¥172.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥364.0 |
| 规格: | 10mg | 产品价格: | ¥509.0 |
| 规格: | 25mg | 产品价格: | ¥794.0 |
| 规格: | 50mg | 产品价格: | ¥1112.0 |
| 规格: | 100mg | 产品价格: | ¥1584.0 |
Product Introduction
Bioactivity
| 名称 | Capmatinib xHCl |
| 描述 | Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM). |
| 体外活性 | Capmatinib hydrochloride 在多种癌症细胞中阻断细胞增殖和迁移或诱导凋亡。[1] |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 4.49 mg/mL (10 mM), Sonication is recommended. |
| 关键字 | U-87MG | SNU-5 | S114 | orally active | Inhibitor | inhibit | INCB-28060 | INCB 28060 | INC-280 | INC 280 | HGFR | H441 | c-Met/HGFR | cMet/HGFR | c-Met | cMet | Capmatinib xHCl | Capmatinib | Balb/c nu/nu mice | ATP competitive | Apoptosis |
| 相关产品 | Formamide | Urea | Sodium Molybdate | Dimethyl phthalate | Aceglutamide | Alginic acid | Cysteamine hydrochloride | Metronidazole | Sildenafil citrate | Citric Acid Triammonium | Stavudine | Tamoxifen |
| 相关库 | Bioactive Compound Library | Anti-Cancer Active Compound Library | Anti-Cancer Approved Drug Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Approved Drug Library | FDA-Approved Drug Library | Membrane Protein-targeted Compound Library | FDA-Approved Kinase Inhibitor Library | Drug Repurposing Compound Library | Anti-Cancer Drug Library |
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化合物 Capmatinib xHCl【1029714-89-3】
¥172 - 1584










