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- 2026年07月07日
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| 规格： | 1mg | 产品价格： | ￥342.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥773.0 |
| 规格： | 10mg | 产品价格： | ￥1149.0 |
| 规格： | 25mg | 产品价格： | ￥1960.0 |
| 规格： | 50mg | 产品价格： | ￥2932.0 |
| 规格： | 100mg | 产品价格： | ￥4364.0 |
| 规格： | 200mg | 产品价格： | ￥5928.0 |
Product Introduction
Bioactivity
| 名称 | [D-Trp34]-Neuropeptide Y Acetate |
| 描述 | [D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats. |
| 体外活性 | [D-Trp34]-Neuropeptide Y Acetate 在 CHO 细胞中对 hY1、hY2、hY4、hY5、rY1、rY2、rY4、rY5 的 pKi 值分别为 6.49、5.43、7.08、7.53、6.55、5.95、6.85、7.41；在 CHO 细胞中对 rY1、rY2 以及在 HEK-293 细胞中对 rY4、rY5 的 pEC50 值分别为 6.44、<6、6.28、7.82[1]。 |
| 体内活性 | [D-Trp34]-Neuropeptide Y Acetate（0、8 和 16 μg/大鼠；I.C.V）在雄性 Zucker 大鼠中注射 16 μg 剂量 1 小时后，对瘦大鼠和肥胖大鼠的食物摄入量具有相同程度的刺激作用[2 ]。 |
| 存储条件 | Store at low temperature,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 关键字 | NeuropeptideYReceptor | Neuropeptide Y Receptor | neuropeptide Y (NPY) Y5 receptor | 153549-84-9 Free base | 153549-84-9 | [D-Trp34]-Neuropeptide Y Acetate |
| 相关产品 | GW438014A | Galanin (1-16), mouse, porcine, rat | JNJ-31020028 | M871 acetate | Pancreatic Polypeptide (human) acetate | (S)-VU0637120 | Galantide acetate | SF 11 | DF-1012 FA | BIIE-0246 | Lu AA33810 | M617 acetate |
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文献和实验Preparation of Carboxypeptidase Y and Its Properties
while high efficiency habit in the scientific research. 【Requirement】 1. Use bread yeast as the original material to extract and condense carboxypeptidase Y, assay its biochemical properties. 2. Through gathering relevant published papers
Characterization of Neuropeptide Y (NPY) Receptors
. Characterization of neuropeptide Y binding sites in rat brain membrane preparations using [125I][Leu31,Pro34]peptide YY and [125I]peptide YY3‐36 as selective Y1 and Y2 radioligands. J. Pharmacol. Exper. Ther. 272:673‐680.
Performing a hunt by interaction mating
, such as the very sensitive pSH18-34, using the lithium acetate method. Select transformants on Glu/CM-Ura,-His plates. Incubate plates at 30o C for 3-4 days until colonies form. Combine 3 colonies for all future tests and for the mating hunt. The bait strain (RFY206
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