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- TargetMol
- T2938
- 2026年07月07日
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- CAS号：
65914-17-2
- 规格：
1g/1mLx10mM(inDMSO)/50mg/100mg/500mg
| 规格： | 1g | 产品价格： | ￥477.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥364.0 |
| 规格： | 50mg | 产品价格： | ￥132.0 |
| 规格： | 100mg | 产品价格： | ￥169.0 |
| 规格： | 500mg | 产品价格： | ￥332.0 |
Product Introduction
Bioactivity
| 名称 | (E/Z)-Polydatin |
| 描述 | (E/Z)-Polydatin (Polydatin), is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, Polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets. Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis. |
| 体外活性 | 在盲肠结扎穿孔诱导的败血症小鼠体内,Polydatin（15/45/100 mg/kg）可抑制CLP诱导的血清TNF-α和IL-6的产生、肺环氧合酶-2和诱导型NO合酶异构体的蛋白质表达及NF-κB活化,从而剂量依赖性降低败血症造成的死亡率和肺损伤.小鼠中Polydatin的LD50为1 g/kg（i.p.）. |
| 体内活性 | Polydatin是一种PLA2抑制剂,可使sPLA2-IIA mRNA表达和磷脂酶A2活性降低,还可使Clara细胞分泌蛋白的表达增加,从而减轻脂多糖诱导的肺部损伤。 |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.12 mM), Sonication is recommended. DMSO : 151.5 mg/mL (388.08 mM), Sonication is recommended. 10% DMSO+90% Saline : 10 mg/mL (25.62 mM), Solution. H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| 关键字 | Polygonum | PLA2 | cuspidatum | (E/Z)-Polydatin | (E/Z)Polydatin | (E/Z) Polydatin |
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| 相关库 | Southwest China Geo-authentic Herb Compound Library | Anti-Cancer Active Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Miao medicine Compound Library | Anti-Tumor Natural Product Library | Anti-Aging Compound Library | Natural Product Library | Cosmetic Ingredient Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS |
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文献和实验E-Z 96 X-press Plasmid Vacuum Protocol
well plate inside the manifold base; 3) Place the top plate of manifold over the base, the deep well plate or waste collection tray now should be positioned under the E-Z 96 X-press Plate. Seal the unused wells of E-Z 96 Xpress Plate with sealing
E-Z 96 X-press Plasmid Spin Protocol
-well plate. Transfer the cell lysate to each well of E-Z 96 X-press plate. 3. Centrifuge at 3000 x g for 5 minutes at room temperature. Discard the flow-through and re-use the deep well plate. 4. Add 500μl DLW Buffer (diluted with isopropanol
E. Z. N.A.TM X-press Plasmid Protocol
实验试剂 Materials to Be Provided by User 1. Ice 2. Isopropanol (100%) 实验设备 Materials to Be Provided by User 1. Tabletop micro-centrifuge capable of 13,000 x g 2. Nuclease Free
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