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5μg/10μg/20μg/50μg/100μg
| 规格: | 5μg | 产品价格: | ¥206.0 |
|---|---|---|---|
| 规格: | 10μg | 产品价格: | ¥300.0 |
| 规格: | 20μg | 产品价格: | ¥490.0 |
| 规格: | 50μg | 产品价格: | ¥971.0 |
| 规格: | 100μg | 产品价格: | ¥1884.0 |
Product Introduction
Bioactivity
| 名称 | Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) |
| 描述 | The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphorylate activated PDGF receptor, thus modulating PDGF-induced mitogenesis. In vitro, LMW-PTP was found to efficiently dephosphorylate activated FcgammaRIIA and LAT, but not Syk or phospholipase Cgamma2. The overexpression of LMW-PTP inhibited activation of Syk downstream of FcgammaRIIA and reduced intracellular Ca(2+) mobilization. It been demonstrated that LMW-PTP is responsible for FcgammaRIIA dephosphorylation, and is implicated in the down-regulation of cell activation mediated by this ITAM-bearing immunoreceptor. In addition, ACP1 is a highly polymorphic phosphatase that is especially abundant in the central nervous system and is known to be involved in several signal transduction pathways. |
| 存储条件 | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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文献和实验我们知道,PeproTech的所有细胞因子和蛋白均为冻干粉,这使得运输非常便捷,只要常温即可。而且,细胞因子和蛋白冻干粉非常稳定,在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解,然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键,因溶解不好会导致细胞因子或蛋白的失活,这也是很多用户在实际使用中经常遇到的问题。 那么,应该如何进行正确的溶解呢? 下面我们以Recombinant Human IL-4 (重组人IL-4,产品编号:200-04)的说明书为例
我们以Recombinant Human IL-4 (重组 人IL-4,产品编号:200-04)的说明书为例,对细胞因子或蛋白的溶解方法进行详细的阐述。 拿到重组 人IL-4的说明书后,您会发现有一段关于Reconstitution(重悬)的叙述,这段内容含有溶解相关的所有信息。 1. Centrifuge the vial prior to opening 第 1 步:开盖前离心试剂管 PeproTech的细胞因子 或蛋白冻干粉装盛在塑料管中,为无菌包装。冻干
大家知道,PeproTech的所有细胞因子和蛋白均为冻干粉,这使得运输非常便捷,只要常温即可。而且,细胞因子和蛋白冻干粉非常稳定,在-20o C或-80o C条件下可保存数年。冻干粉在使用前需进行溶解,然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键,因溶解不好会导致细胞因子或蛋白的失活,这也是很多用户在实际使用中经常遇到的问题。 应该如何进行正确的溶解呢? 下面我们以Recombinant Human IL-4 (重组人IL-4,产品编号:200-04
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