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- 文献和实验
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- CAS号:
585-99-9
- 规格:
1mLx10mM(inDMSO)/20mg
| 规格: | 1mLx10mM(inDMSO) | 产品价格: | ¥128.0 |
|---|---|---|---|
| 规格: | 20mg | 产品价格: | ¥102.0 |
Product Introduction
Bioactivity
| 名称 | D-Melibiose |
| 描述 | D-Melibiose (Galalpha1-6Glcbeta) is a reducing disaccharide formed by an alpha-1, 6 linkage between galactose and glucose (D-Gal-α(1→6)-D-Glc). |
| 存储条件 | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 62.5 mg/mL (182.59 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.84 mM), Sonication is recommended. 10% DMSO+90% Saline : 6.25 mg/mL (18.26 mM), Solution. |
| 关键字 | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | D-Melibiose | DMelibiose | D Melibiose |
| 相关产品 | Formamide | Guanidine hydrochloride | Glycerol | Aceglutamide | Malic acid | DL-Lysine | Sucrose | Nicotinamide riboside malate | Gluconate Calcium | Thymidine | Corn starch | D(+)-Raffinose pentahydrate |
| 相关库 | Food Sourced Compound Library | Selected Plant-Sourced Compound Library | Covalent Natural Product Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Cosmetic Ingredient Compound Library | Natural Product Library | Tobacco Monomer Library | Chinese Pharmacopoeia Natural Product Library | Saccharide and Glycoside Natural Product Library | Natural Product Library for HTS | Human Metabolite Library |
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文献和实验by the fluorescene and UV spectrograph after one hour water bath (37.0 oC). We did not find distinct changes at the characteristic peaks of DNA, 260 nm in UV spectrum and 585 nm in fluorescene spectrum (excitation wavelength is 365.0 nm). From the spectra (Figure
分,分别是可溶性的 sAPPβ 和膜结合的 C99 片段 (CTFβ)。 • 第二步:γ-分泌酶复合物登场。这个复合物由 PS1/PS2、NCT、PEN2、APH1 四种蛋白组成,它会进一步切割 C99 片段,最终产生两种产物:Aβ 蛋白和 APP 胞内结构域 (AICD)[1]。 图 1. Aβ 的产生[1]。 新生成的 Aβ 蛋白单体并不安分,它们会自发“抱团”。先是组装成可溶性的 Aβ 寡聚体 (AβOs) 和原纤维,最终聚集形成不溶性的纤维沉淀,也就是我们常说的 Aβ 斑块。 值得
1)为了在SG反应后作溶解曲线,引入与溶解曲线起始温度点相同的保温步骤(大约60秒),这样可以确保溶解温度起始于一个确定的温度。2)溶解曲线分析可以重复。可以在相当一段时间内重新作溶解曲线,甚至到第二天也可以。3)关于可以用SG检测的引物对的列表4) 进行SG分析的典型程序是什么?变性:检查反应所用的酶(2min,5min,10min或15min)循环:95度/20秒,退火温度/20秒,72度/20秒保温:72度/60秒溶解:72-99度,on Melt A5)在哪个通道SG可以被检测?双通道
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