Collagen Type XI Polyclonal an

【产品概述】
本产品为Collagen Type XI Polyclonal antibody（货号：21841-1-AP），由Rabbit / IgG宿主制备。该抗体属于Polyclonal抗体，可识别human来源的靶蛋白，经测试适用于WB, IHC, IF-P, ELISA等实验应用。产品形式为Liquid，偶联物类型为Unconjugated。

【背景介绍】
COL11A1 is an important component of collagen XI and is considered to play an important role in a variety of connective tissue diseases. Type XI collagen is widely distributed in tissues including cartilage, bone, and muscle, and its hereditary absence in Marshall's syndrome, Stickler's syndrome, fibrochondrogenesis, and nonsyndromic hearing loss deafness, autosomal dominant 37 leads to facial and eye abnormalities, hearing loss, and joint problems. The COL11A1 expression was significantly correlated with the degree of immune infiltration and the expression of a variety of immune cell markers in tumor tissue. (PMID: 36160004 33610546)

【产品特点】
本抗体采用Antigen affinity purification方式纯化，确保了高特异性和批次间一致性。观测分子量约为250 kDa, 181 kDa。推荐稀释比：WB: WB : 1:500-1:2000；IHC: IHC : 1:50-1:500。Western Blot检测阳性对照组织/细胞为U2OS cells。储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.，储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.。Proteintech抗体经过严格的质量验证流程，确保研究人员获得可重复且可靠的实验结果。

【产品信息】
GenBank蛋白编号：BC117697；基因名称：COL11A1；Gene ID (NCBI)：1301；UNIPROT ID：P12107；RRID：AB_2918074；别名包括：COL11, COL11A1, CO11A1, COLL6, Collagen alpha 1(XI) chain；免疫原为CatNo:Ag16509Product name: Recombinant human COL11A1 proteinSource:e coli.-derived, PGEX-4TTag: GSTDomain: 1429-1690 aa ofBC117697Sequence: PLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG种属同源性预测；储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.，储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.；产品形式为Liquid；纯化方式为Antigen affinity purification。