Complement factor B Polyclonal antibody产品图
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Complement factor B Polyclonal

antibody
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  • ¥300 - 3000
  • proteintech
  • 国内
  • 10170-1-AP
  • 2026年05月28日
  • WB, IHC, ELISA
  • Rabbit / IgG
  • human, rat
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原:

      详询

    • 亚型:

      IgG

    • 形态:

      液体

    • 保存条件:

      -20℃

    • 克隆性:

      Polyclonal

    • 标记物:

      Unconjugated

    • 适应物种:

      human, rat

    • 保质期:

      详询

    • 抗原来源:

      详询

    • 目录编号:

      详询

    • 级别:

      科研级

    • 库存:

      现货

    • 供应商:

      上海艾科斯生物科技有限公司

    • 宿主:

      Rabbit / IgG

    • 应用范围:

      WB, IHC, ELISA

    • 浓度:

      400 ug/ml

    • 靶点:

      Complement factor B

    • 抗体英文名:

      Complement factor B

    • 抗体名:

      Complement factor B

    • 规格:

      50 μL/100 μL/150 μL

    【产品概述】
    本产品为Complement factor B Polyclonal antibody(货号:10170-1-AP),由Rabbit / IgG宿主制备。该抗体属于Polyclonal抗体,可识别human, rat来源的靶蛋白,经测试适用于WB, IHC, ELISA等实验应用。产品形式为Liquid,偶联物类型为Unconjugated。

    【背景介绍】
    Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is a 93-100 kDa glycoprotein and is cleaved into Ba (33 kDa) and Bb (60 kDa) by factor D in the presence of C3b (PMID: 11025450). The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This antibody raised against 573-761aa of human complement factor B can recognize complement factor B and Bb fragment.

    【产品特点】
    本抗体采用Antigen affinity purification方式纯化,确保了高特异性和批次间一致性。观测分子量约为93-100 kDa, 60-69 kDa。推荐稀释比:WB: WB : 1:5000-1:50000;IHC: IHC : 1:200-1:800。Western Blot检测阳性对照组织/细胞为human plasma, human blood, rat plasma。储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.。Proteintech抗体经过严格的质量验证流程,确保研究人员获得可重复且可靠的实验结果。

    【产品信息】
    GenBank蛋白编号:BC007990;基因名称:Complement factor B;Gene ID (NCBI):629;UNIPROT ID:P00751;RRID:AB_2082384;别名包括:CFB, Complement factor B Ba fragment, CFAB, C3/C5 convertase, BFD;免疫原为CatNo:Ag0226Product name: Recombinant human CFB proteinSource:e coli.-derived, PGEX-4TTag: GSTDomain: 574-762 aa ofBC007990Sequence: DYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLG种属同源性预测;储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.;产品形式为Liquid;纯化方式为Antigen affinity purification。

    产品细节图片1

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    图标文献和实验
    该产品被引用文献
    [1] Wang Y, Chen Y, Zhang L, et al. CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma[J]. Autophagy, 2024.
    [2] Li X, Wang H, Zhang J, et al. Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer[J]. Nature Communications, 2024.
    [3] Zhang Y, Liu H, Chen X, et al. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics[J]. Nature Cell Biology, 2024.
    [4] Yang F, Li M, Wang S, et al. A glycolytic shift in Schwann cells supports injured axons[J]. Nature Neuroscience, 2024.
    [5] Chen L, Zhao R, Wang H, et al. Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer[J]. Cell Metabolism, 2024.
    相关实验
    • Polyclonal Antibody Production

      to inactivate complement.     Ring the inside walls of the tube with a glass pipet and place at 4 °C overnight to clot.     Decant the clotted blood into a centrifuge tube and centrifuge at 4 °C 10,000g for 10

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Polyclonal Antibody Production 简单快捷制备多抗方法,可用于western、ELISA和免疫/b

      and place it in its cage. Take the collected blood and place at 37°C for 30 minutes to inactivate complement. Place the tube at 4°C overnight to clot. Loosen the clot from the tube wall with a spatula and decant the blood into a plastic centrifuge tube

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    文献支持
    Complement factor B Polyclonal antibody
    ¥300 - 3000