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c-SRC Polyclonal antibody

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  • ¥300 - 3000
  • proteintech
  • 国内
  • 11097-1-AP
  • 2026年05月11日
  • WB, IHC, IF/ICC, IP, ELISA
  • Rabbit / IgG
  • human, mouse, rat, hamster
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      详询

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      -20℃

    • 克隆性

      Polyclonal

    • 标记物

      Unconjugated

    • 适应物种

      human, mouse, rat, hamster

    • 保质期

      详询

    • 抗原来源

      详询

    • 目录编号

      详询

    • 供应商

      上海艾科斯生物科技有限公司

    • 宿主

      Rabbit / IgG

    • 应用范围

      WB, IHC, IF/ICC, IP, ELISA

    • 浓度

      400 ug/ml

    • 靶点

      c-SRC

    • 抗体英文名

      c-SRC

    • 抗体名

      c-SRC

    • 规格

      50 μL/100 μL/150 μL

    【产品概述】
    本产品为c-SRC Polyclonal antibody(货号:11097-1-AP),由Rabbit / IgG宿主制备。该抗体属于Polyclonal抗体,可识别human, mouse, rat, hamster来源的靶蛋白,经测试适用于WB, IHC, IF/ICC, IP, ELISA等实验应用。产品形式为Liquid,偶联物类型为Unconjugated。

    【背景介绍】
    SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase. SRC can be detected as 60 kDa and 55 kDa (PMID: 15047935, 21461171).

    【产品特点】
    本抗体采用Antigen affinity purification方式纯化,确保了高特异性和批次间一致性。观测分子量约为55 kDa, 60 kDa。推荐稀释比:WB: WB : 1:500-1:3000;IHC: IHC : 1:100-1:400;IP: IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate。Western Blot检测阳性对照组织/细胞为HUVEC cells, mouse brain tissue, COLO 320 cells, A431 cells, Jurkat cells, CHO cells, SH-SY5Y cells, HepG2 cells。储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.。Proteintech抗体经过严格的质量验证流程,确保研究人员获得可重复且可靠的实验结果。

    【产品信息】
    GenBank蛋白编号:BC011566;基因名称:SRC;Gene ID (NCBI):6714;UNIPROT ID:P12931;RRID:AB_2286705;别名包括:SRC, c SRC, cSRC, EC:2.7.10.2, p60-Src;免疫原为CatNo:Ag1575Product name: Recombinant human c-SRC proteinSource:e coli.-derived, PGEX-4TTag: GSTDomain: 187-536 aa ofBC011566Sequence: YCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL种属同源性预测;储存缓冲液为PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.,储存条件为Store at -20°C. Stable for one year after shipment.Aliquoting is unnecessary for -20oC storage.;产品形式为Liquid;纯化方式为Antigen affinity purification。

    产品细节图片1

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    图标文献和实验
    该产品被引用文献
    [1] Wang Y, Chen Y, Zhang L, et al. CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma[J]. Autophagy, 2024.
    [2] Li X, Wang H, Zhang J, et al. Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer[J]. Nature Communications, 2024.
    [3] Zhang Y, Liu H, Chen X, et al. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics[J]. Nature Cell Biology, 2024.
    [4] Yang F, Li M, Wang S, et al. A glycolytic shift in Schwann cells supports injured axons[J]. Nature Neuroscience, 2024.
    [5] Chen L, Zhao R, Wang H, et al. Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer[J]. Cell Metabolism, 2024.
    相关实验
    • Polyclonal Antibody Production

      . If you used xylene, rinse two or three times with ethanol to remove it.     Remove the rabbit from the restrainer and place in its cage.     Take the collected blood and place at 37 °C for 30 minutes

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Construction of Polyclonal Antibody Libraries Using Phage Display

      Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified

    图标技术资料

    暂无技术资料 索取技术资料

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    文献支持
    c-SRC Polyclonal antibody
    ¥300 - 3000