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重组蛋白 CD37 hFc Chimera 人 hFc

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  • ¥3000 - 9900
  • 上海经科
  • 中国
  • JK8114
  • 2026年05月21日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -20℃

    • 保质期

      3 months at -20°C

    • 英文名

      CD37 hFc Chimera, Human

    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      100μg/500μg

    规格:100μg产品价格:¥3000.0
    规格:500μg产品价格:¥9900.0
    产品简介
    Species Human
    Protein Construction
    hFc CD37 (Ala113-Asn240)
    Accession # P11049-1
    N-term C-term
    Purity > 95% as determined by BisTris PAGE
    Endotoxin Level Less than 1EU per μg by the LAL method.
    Expression System HEK293
    Theoretical Molecular Weight 41.9 kDa
    Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
    Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
    Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
    Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
    技术背景
    Target Background CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
    Synonyms Tetraspanin-26; Tspan-26; CD37; CD37 molecule; GP52-40; MGC120234

    产品特点:

    1. 【人源天然序列】采用人源 CD37 天然氨基酸序列,无突变,与体内天然蛋白结构完全一致,可特异性结合 CD37 配体2. 【高活性高特异性】可特异性结合 CD37 抗体,ED₅₀ < 100 ng/mL(抗体结合实验),可被 CD37 特异性抗体识别,适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.2 EU/μg(LAL 法),适配免疫细胞培养、体内免疫实验等敏感场景需求4. 【Fc 融合易纯化检测】C 端带人 IgG1 Fc 标签,可通过 Protein A/G 亲和层析快速纯化,也可通过 Fc 标签抗体进行特异性检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 CD37 蛋白结构与功能研究、免疫调控与炎症机制研究、肿瘤免疫治疗研究、细胞培养添加剂、药物筛选、抗体研发等

    CD37, 人源,人,重组蛋白,重组,高活性,高纯度,低内毒素,hFc 融合蛋白,细胞培养,免疫细胞,科研实验,哺乳动物细胞表达 Human,CD37,Recombinant protein,hFc chimera,High activity,High purity,Low endotoxin,Cell culture,Immune cell,Mammalian expression

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    图标文献和实验
    该产品被引用文献
    CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
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    文献支持
    重组蛋白 CD37 hFc Chimera 人 hFc
    ¥3000 - 9900