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- 技术资料
- 保存条件:
-20℃
- 保质期:
3 months at -20°C
- 英文名:
CD37 hFc Chimera, Human
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 规格:
100μg/500μg
| 规格: | 100μg | 产品价格: | ¥3000.0 |
|---|---|---|---|
| 规格: | 500μg | 产品价格: | ¥9900.0 |
| Species | Human | ||||
| Protein Construction |
|
||||
| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 41.9 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients. |
| Synonyms | Tetraspanin-26; Tspan-26; CD37; CD37 molecule; GP52-40; MGC120234 |
产品特点:
1. 【人源天然序列】采用人源 CD37 天然氨基酸序列,无突变,与体内天然蛋白结构完全一致,可特异性结合 CD37 配体2. 【高活性高特异性】可特异性结合 CD37 抗体,ED₅₀ < 100 ng/mL(抗体结合实验),可被 CD37 特异性抗体识别,适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.2 EU/μg(LAL 法),适配免疫细胞培养、体内免疫实验等敏感场景需求4. 【Fc 融合易纯化检测】C 端带人 IgG1 Fc 标签,可通过 Protein A/G 亲和层析快速纯化,也可通过 Fc 标签抗体进行特异性检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 CD37 蛋白结构与功能研究、免疫调控与炎症机制研究、肿瘤免疫治疗研究、细胞培养添加剂、药物筛选、抗体研发等
CD37, 人源,人,重组蛋白,重组,高活性,高纯度,低内毒素,hFc 融合蛋白,细胞培养,免疫细胞,科研实验,哺乳动物细胞表达 Human,CD37,Recombinant protein,hFc chimera,High activity,High purity,Low endotoxin,Cell culture,Immune cell,Mammalian expression
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