- ￥300 - 600
- 上海经科
- JK7695
- 2026年05月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 英文名：
HRG1-β1, Human
- 供应商：
上海经科化学科技有限公司
- 规格：
10μg/50μg
| 规格： | 10μg | 产品价格： | ￥300.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥600.0 |
| Species | Human | |
| Protein Construction |
Expressed with an N-terminal Met.
|
|
| Purity | > 95% as analyzed by SDS-PAGE | |
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
| Biological Activity | ED50 < 1.0 ng/ml, measured by a cell proliferation assay using MCF-7 cells, corresponding to a specific activity of > 1.0 × 106 U/mg. | |
| Expression System | E. coli | |
| Apparent Molecular Weight | ~7.6 kDa, on SDS-PAGE under reducing conditions. | |
| Formulation | Lyophilized after extensive dialysis against PBS. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for 6 months at lower than -70°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
| Target Background | Heregulin1-Beta1(HRG1-Beta1) is one of the isoforms encoded by Neuregulin (NRG) genes. NRGs are synthesized as large transmembrane precursor proteins, and the NRG family has 4 members and 26 isoforms. These isoforms provide large diversities, including different tissue distribution, variable potencies, and different biological functions. HRG1-β1 belongs to Type I HRG1, and is expressed in neural tissue, respiratory epithelia, and heart. In vivo, HRG1 binds and activates both ErbB3 and ErbB4, the transmembrane receptor tyrosine kinase, and is involved in the proliferation, differentiation, and survival of cells. Aberrantly produced HRG1 could be used in the constitute activation of the ErbB receptors; therefore, the upregulation of HRG1 contributes to the development of tumors, including breast cancer. |
| Synonyms | Neuregulin1; NRG1-β1 |
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文献和实验bigqi 我正在做一个蛋白的研究，多篇文章提到它可以作用于NRG，有NRG 1，有NRG beta 1. 我搞不清楚到底beta 1属于那种NRG。 我查了综述，是将NRG分为1、2、3、4的，没有找到NRG beta，请问beta＝2吗？还是beta 1＝1 beta？感觉都不太像。 当然也可能是看的太快，又是英文的综述，漏掉了作者的解释。 NRG不是我要研究的内容，不想花更多时间了，请问能否有人可以帮我，我就想知道我的蛋白
factor-beta (TGF-β1) and elucidate its mechanism in fibrosis. METHODS: The proliferation, morphology and expression of TGF-β1 of fibroblast was measured by MTT bioassay, HE dyeing and immunocytochemistry. RESULTS: The kwoninone has an could significantly
常见蛋白质等电点参考值 蛋白质 等电点 鲑精蛋白[salmine] 12.1 鲱精蛋白[clupeine] 12.1 鲟精蛋白[sturline] 11.71 胸腺组蛋白[thymohistone] 10.8 珠蛋白（人）[globin(human)] 7.5 卵白蛋白[ovalbuin] 4.71；4.59 伴清蛋白[conal bumin] 6.8，7.1 血清白蛋白[serum albumin] 4.7－4.9 肌清蛋白[myoal
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