- ￥5800 - 19200
- 上海经科
- JK8880
- 2026年05月09日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 英文名：
LAIR1/CD305[Biotin], His & Avi, Human
- 供应商：
上海经科化学科技有限公司
- 规格：
100μg/500μg
| 规格： | 100μg | 产品价格： | ￥5800.0 |
|---|---|---|---|
| 规格： | 500μg | 产品价格： | ￥19200.0 |
| Species | Human | ||||||
| Protein Construction |
|
||||||
| Conjugate | Biotin | ||||||
| Purity | > 95% as determined by BisTris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 18.2 kDa | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. |
| Synonyms | CD305; HLAIR1; LAIR1; LAIR-1 |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验不只是 PD-1：CD96 正成为免疫治疗的下一个“必争之地”
价值。华美生物提供CD96重组蛋白、抗体及ELISA试剂盒产品，助力您进行相关机制研究及靶向药物开发。 ● CD96 重组蛋白 Recombinant Human T-cell surface protein tactile (CD96), partial (Active); CSB-MP004971HU1(F2) ● CD96 抗体 CD96 Recombinant Monoclonal Antibody; CSB-RA004971A0HU ● CD96 ELISA 试剂
Nature 重磅：新发脑胶质瘤疫苗初见成效，瞄准肿瘤「阿喀琉斯之踵」
1-VAc 诱导的免疫应答。其中，26 名患者观察到 IDH1-vac 诱导的 T 细胞免疫反应，28 名患者观察到跨越多个人类白细胞抗原 (HLA) 等位基因的 B 细胞免疫反应。但是还有 2 名患者 (6.7%) 既没有出现 T 细胞免疫反应，也没有出现 B 细胞免疫反应。 因此，IDH1-vac 疫苗可以有效诱导机体产生 IDH1 特异性的免疫应答反应，提示新抗原 IDH1（R132H）具有良好的免疫原性。 图片来源：Nature 在疗效方面，患者的总体反应率（overall response
%的SDS-PAGE分析，在分子量28KD和26KD各有一条蛋白带，经扫描分析28 KD的蛋白占纯化产物的62.97%，26KD的蛋白占纯化产物的33.13%。Western blot结果表明，抗E-tag抗体只能与带有E-tag片段的分子量为28KD的蛋白带杂交，而与分子量为26 KD的蛋白带无特异性反应。3、大小排阻层析抗CD3/抗Pgp Diabody，抗PgpScFv的滞留时间分别为77.29min，90.10 min。抗CD3/抗Pgp Diabody主峰含量≥90%，而分子量为66 KD
技术资料暂无技术资料 索取技术资料
