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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉研升生物科有限公司
- 检测范围:
15.63-1000 pg/mL
- 检测方法:
Sandwich
- 适应物种:
Rat
- 样本:
Serum, plasma, tissue homogenates and other biological fluids
- 灵敏度:
5.7 pg/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1820.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2600.0 |
| 中文名称 | 大鼠骨成型蛋白2(BMP2)微量上样酶联免疫吸附检测试剂盒 |
| 英文名称 | Rat BMP2(Bone Morphogenetic Protein 2) Microsample ELISA Kit |
| 别名 | BMP2A; BMP-2A; Hemochromatosis Modifier |
| 货号 | ELK1405MS |
| 反应种属 | Rat |
| P49001 | P49001 |
| 检测类型 | Sandwich |
| 灵敏度 | 5.7 pg/mL |
| 标准品 | 1000 pg/mL |
| 检测范围 | 15.63-1000 pg/mL |
| 样本类型 | Serum, plasma, tissue homogenates and other biological fluids |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat BMP2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat BMP2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat BMP2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat BMP2 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Developmental science;Bone metabolism; |

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文献和实验-β)1、2、3,骨形态发生蛋白(bone morphogenetic protein,BMP)2、6、9、13,胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1),软骨源性发生蛋白cartilage-derived morphogenetic protein,CDMP)1、2及地塞米松等。TGF-β主要作用于诱导的早期阶段,一般认为通过其受体激活Smad传导通路而启动软骨特异性基因的转录,主要是上调Ⅱ型胶原的表达与合成。BMP2、6等则可明显增强聚集蛋白
Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN
in the gene bmp2b . View Image Figure 1.18.18 A portion of the Mutant/Morphant/Transgenics Search
Clin Invest. 2009 简介: 中南大学第二湘雅医院的研究人员发现,miR-2861可通过转录后水平抑制HDAC5的表达而促进小鼠成骨细胞分化。在BMP2诱导的骨形成模型中,miR-2861由ST2间质细胞表达,并促进BMP2诱导的成骨细胞生成,而抑制miR-2861则可削弱这个作用。在正常小鼠及卵巢切除小鼠模型中,利用micrOFFTM antagomir-2861抑制miR-2861的表达,可引起HDAC5的表达上调和RUNX2的表达下调,并抑制骨形成和减少骨质
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