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Haptoglobin Rabbit Polyclonal

Antibody
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  • ¥1200 - 2150
  • EnkiLife
  • APRab11899
  • 2026年04月17日
  • IHC,ICC/IF,ELISA
  • Rabbit
  • Human,Rat,Mouse
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 形态

      Liquid

    • 保存条件

      Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    • 标记物

      Unconjugated

    • 适应物种

      Human,Rat,Mouse

    • 供应商

      武汉恩玑生命科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC,ICC/IF,ELISA

    • 规格

      50uL/100uL

    规格:50uL产品价格:¥1200.0
    规格:100uL产品价格:¥2150.0

    产品概述

    产品名称(Product Name)

    Haptoglobin Rabbit Polyclonal Antibody

    描述(Description)

    Rabbit polyclonal Antibody

    宿主(Host)

    Rabbit

    应用(Application)

    IHC,ICC/IF,ELISA

    种属反应性(Reactivity)

    Human,Rat,Mouse

     

    产品性能

    偶联物(Conjugation)

    Unconjugated

    修饰(Modification)

    Unmodified

    同种型(Isotype)

    IgG

    克隆(Clonality)

    Polyclonal

    形式(Form)

    Liquid

    存放说明(Storage)

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    储存溶液(Buffer)

    Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

    纯化方式(Purification)

    Affinity purification

     

    免疫原

    基因名(Gene Name)

    HP

    别名(Alternative Names)

    Haptoglobin (Zonulin) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain]

    基因ID(Gene ID)

    3240

    蛋白ID(SwissProt ID)

    P00738

     

    产品应用

    稀释比(Dilution Ratio)

    IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

    蛋白分子量(Molecular Weight)

     

    研究背景

    haptoglobin(HP) Homo sapiens This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located nexcaution:Although homologous to serine proteases, it has lost all essential catalytic residues and has no enzymatic activity.,function:Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.,online information:Haptoglobin entry,online information:The Singapore human mutation and polymorphism database,polymorphism:In the human populations there are two major allelic forms, alpha-1 with 83 residues and alpha-2 with 142 residues. These alleles determine the 3 major phenotypes HP*1F/HP*1S and HP*2FS. The two main alleles of HP*1 are called HP*1F (fast) and HP*1S (slow).,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Tetramer of two alpha and two beta chains.,tissue specificity:Expressed by the liver and secreted in plasma.,tissue specificity:In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in hepatoma G2 and leukemia molt-4 cell lines.,

     

    研究领域

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      Zealand White Rabbits and have them delivered to the ARC. Don’t put all your eggs in one basket only using one rabbit. Let them get accustomed to there home there for two weeks before the first pre-bleed. Pre-bleed        

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Generation and Selection of Rabbit Antibody Libraries by Phage Display

      The rabbit antibody repertoire is an exceptional source for both polyclonal antibodies (pAbs) and monoclonal antibodies (mAbs) that combine high specificity with high avidity and affinity, respectively. In contrast to rabbit pAbs

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