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- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
12 months
- 英文名:
Research Grade Anti-Human CD318/CDCP1 (RG7287)
- 供应商:
武汉益普生物科技有限公司
- 规格:
100μg/1mg
| 规格: | 100μg | 产品价格: | ¥572.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥1480.0 |
| 产品名称 | Research Grade Anti-Human CD318/CDCP1 (RG7287) |
| 货号 | HV451016 |
| 描述 | Anti-Human CD318/CDCP1 (RG7287) ( HV451016 ) is a research-grade recombinant antibody targeting CD318 . Produced in mammalian cells with native-like glycosylation. Highlights Research Grade — For PK/PD studies, assay development, and ADA research. Native Glycosylation — Mammalian expression ensures native-like patterns. |
| 反应种属 | Human |
| 应用实验 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主/表达体系 | Human |
| 靶点 | CD318, Transmembrane and associated with src kinases, TRASK, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Membrane glycoprotein gp140, CUB domain-containing protein 1, CDCP1 |
| 基因号 | Q9H5V8 |
| 状态 | Liquid |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 储存温度 | -20℃ |
| 别名 | RG7287 |

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文献和实验) A431 cells. At 48 h after infection, these cells were stained with ten different primary antibodies (5 g/ml) specific for different cell surface markers: anti-CD15 (clone 2F3; BD, PharMingen, San Diego, CA), anti-ERBB-2 (clone SP77; ref. 5), anti-ERBB
Human Complement Components C4A and C4B Genetic Diversities: Complex Genotypes and Phenotypes
) Hemoglobin marker: 1 g lyophilized human hemoglobin (Sigma) resuspended in 600 µl PBS Goat anti–human C4 (DiaSorin)
水平。结论嵌合抗CD20抗体片段Fab’能抑制Raji细胞生长和诱导细胞凋亡,其作用机制与bcl-2蛋白表达的下降有关。【关键词】抗CD20抗体 B淋巴瘤 Bcl-2【中图分类号】R318 R733CD20对B淋巴细胞的分化增殖具有调节作用[ 1 ] 。CD20是治疗B淋巴细胞瘤的理想靶点。CD20在前B细胞及成熟B细胞中有表达,而浆细胞、造血干细胞及T细胞则无CD20的表达;CD20比较暴露不为其它表面分子所掩盖,易与抗体结合;CD20和抗CD20抗体结合后不发生内吞作用,因而细胞表面CD20数量并不
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