- ￥598 - 2488
- abinScience
- France
- HW342016
- 2026年04月12日
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Human
- Human
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- 详细信息
- 技术资料
- 亚型：
IgG2-kappa
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
12 months
- 级别：
一抗
- 供应商：
武汉益普生物科技有限公司
- 宿主：
Human
- 应用范围：
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- 抗体英文名：
Research Grade Ivuxolimab
- 规格：
100μg/1mg
| 规格： | 100μg | 产品价格： | ￥598.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥2488.0 |
| 产品名 | Research Grade Ivuxolimab |
| 货号 | HW342016 |
| 别名 | PF-04518600, 2225940-98-5 |
| 表达系统 | Mammalian Cells |
| 靶标 | ACT35 antigen, TXGP1L, TAX transcriptionally-activated glycoprotein 1 receptor, Tumor necrosis factor receptor superfamily member 4, TNFRSF4, OX40L receptor, CD134 |
| Accession号 | P43489 |
| 宿主 | Human |
| 种属反应性 | Human |
| 克隆性 | Monoclonal |
| 同种型 | IgG2-kappa |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Ivuxolimab (PF-04518600) is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response • Targeting co-stimulatory molecules in autoimmune disease., PMID:32939077 • OX40 in the Pathogenesis of Atopic Dermatitis-A New Therapeutic Target., PMID:38236520 • The role of OX40 ligand/OX40 axis signalling in atopic dermatitis., PMID:38836560 • Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists., PMID:39636970 • An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis., PMID:38607026 • Entry of betaherpesviruses., PMID:31439151 • OX40 (CD134) and OX40L., PMID:19760068 • Research progress in OX40/OX40L in allergic diseases., PMID:39404736 • The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8+ T-cell immunity., PMID:37932534 • The role of tumor necrosis factor receptor superfamily member 4 (TNFRSF4) gene expression in diagnosis and prognosis of acute myeloid leukemia., PMID:34453673 |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |
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Ivuxolimab
￥598 - 2488
