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- 2026年04月12日
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文献和实验Immortalised cultured cells are powerful tools to assess the function of ectopically expressed proteins. However, it must be ensured that the protein of interest is functional in the host system and display native behaviour. In particular
of downstream signaling pathways. Key to understanding this process is the study of the protein–protein interactions involving R proteins. Recognition and signaling mechanisms are mediated by both intramolecular interactions that take place between different
Expressing Full-Length Functional PfEMP1 Proteins in the HEK293 Expression System
weight, which further complicates expression of these proteins in heterologous systems. The high molecular weight Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) adhesins expressed on the surface of the infected erythrocytes
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