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文献和实验antigens (Ag) complexed to MHC class I molecules (6 ,7 ). Immunization with virus-infected antigen-presenting cells (APC) or Ag-expressing transfectants, and even APC osmotically loaded with antigens can elicit CD8+ cytotoxic T-cells (8 –10
Staphylococcus enterotoxin superantigens (SAgs) have the capacity to strongly activate oligoclonal populations of T lymphocytes expressing T-cell antigen receptors (TCR) that share particular Vβ elements. These superantigens stimulate T
Protein Therapeutics: Mouse, Humanized, and Human Antibodies
component of the vertebrate immune system. Each plasma cell secretes a single clone of antibodies that bind a unique epitope of an antigen. Cooperations exist between antibodies and other immune effectors such as macrophages and complement to facilitate
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