- ￥2968 - 8888
- abinScience
- France
- HC359336
- 2026年04月13日
- ELISA, Functional assay, Research in vivo
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Fusion - SIRPA (signal regulatory protein alpha, SHPS1, SIRP, SIRPalpha) - IGHG1 (Fc (Fragment constant)
- 形态：
Liquid
- 保存条件：
-20°C
- 适应物种：
Human
- 保质期：
12 months
- 级别：
一抗
- 供应商：
武汉研升生物科技有限公司
- 应用范围：
ELISA, Functional assay, Research in vivo
- 抗体英文名：
Research Grade Ontorpacept
- 规格：
100μg/1mg
| 规格： | 100μg | 产品价格： | ￥2968.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥8888.0 |
| 产品名 | Research Grade Ontorpacept |
| 货号 | HC359336 |
| 别名 | TTI-621, TTI-621-01, 2131089-46-6 |
| 表达系统 | Mammalian Cells |
| 靶标 | Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6 |
| Accession号 | Q08722 |
| 种属反应性 | Human |
| 同种型 | Fusion - SIRPA (signal regulatory protein alpha, SHPS1, SIRP, SIRPalpha) - IGHG1 (Fc (Fragment constant) |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Magrolimab is a first-in-class investigational monoclonal antibody against CD47 and macrophage checkpoint inhibitor that is designed to interfere with recognition of CD47 by the SIRPα receptor on macrophages, thus blocking the • Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3., PMID:7998989 • Integrin-associated protein (CD47) and its ligands., PMID:11306274 • Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow., PMID:11156950 • Rh-related antigen CD47 is the signal-transducer integrin-associated protein., PMID:8294396 • Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling., PMID:16697668 • Integrin-associated protein/CD47 regulates motile activity in human B-cell lines through CDC42., PMID:10891456 • Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells., PMID:8992983 • Molecular cloning and functional characterization of the pig homologue of integrin-associated protein (IAP/CD47)., PMID:12153520 • Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain., PMID:12736272 • The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi., PMID:10085089 |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |
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文献和实验Characterization and Quality Control of Antibodies Used in ChIP Assays
epigenetics research tools based on everyday’s researcher’s needs by providing batch-specific fully characterized ChIP-grade antibodies.
相关专题 his method was successful in our lab using prostate tissue and for our specific objectives. Investigators must be aware that they will need to tailor the following protocol for their own research objectives
®尤其在皮肤组织的表皮分离和上皮层细胞培养中获得了广泛的应用。Dispase®I与Dispase®II两者的差别在于纯度的不同，Dispase®I经过滤除菌，且每mg Dispase®I的纯度和酶活远高于Dispase®II。 罗氏高纯度研究级别酶混合物Liberase Research Grade Enzyme Blends Liberase Research Grade Enzyme Blends包含了一系列酶混合物，它们由不同比例的中性蛋白酶（非梭菌蛋白酶）和高纯
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