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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG4-kappa
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
单克隆
- 适应物种:
Human
- 保质期:
12 months
- 级别:
一抗
- 供应商:
武汉研升生物科技有限公司
- 宿主:
Human
- 应用范围:
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- 抗体英文名:
Research Grade Acrixolimab
- 规格:
100μg/1mg
| 规格: | 100μg | 产品价格: | ¥2288.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥6788.0 |
| 产品名 | Research Grade Acrixolimab |
| 货号 | HS870156 |
| 别名 | YBL006, YBL-006, YBL006, 2506324-29-2 |
| 表达系统 | Mammalian Cells |
| 靶标 | Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279 |
| Accession号 | Q15116 |
| 宿主 | Human |
| 种属反应性 | Human |
| 克隆性 | Monoclonal |
| 同种型 | IgG4-kappa |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 状态 | Liquid |
| 背景 | Balstilimab is a novel, fully human monoclonal immunoglobulin G4 (IgG4) designed to block PD-1 (programmed cell death protein 1) from interacting with its ligands PD-L1 and PD-L2. PD-1 is a negative regulator of immune activation that is considered a foundational target within the immuno-oncology market. • The blockade of immune checkpoints in cancer immunotherapy., PMID:22437870 • PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations., PMID:30888929 • The diverse functions of the PD1 inhibitory pathway., PMID:28990585 • PD-1/PD-L1 immune checkpoint: Potential target for cancer therapy., PMID:30191996 • Immune Checkpoint Blockade in Cancer Therapy., PMID:25605845 • PD-1 expression and clinical PD-1 blockade in B-cell lymphomas., PMID:29118007 • Overcoming T cell exhaustion in infection and cancer., PMID:25797516 • Study and analysis of antitumor resistance mechanism of PD1/PD-L1 immune checkpoint blocker., PMID:32875727 • Tumor Mutational Burden and Response Rate to PD-1 Inhibition., PMID:29262275 • PD-L1., PMID:29097600 |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 说明 | For research use only. Not suitable for clinical or therapeutic use. |

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文献和实验Characterization and Quality Control of Antibodies Used in ChIP Assays
epigenetics research tools based on everyday’s researcher’s needs by providing batch-specific fully characterized ChIP-grade antibodies.
相关专题 his method was successful in our lab using prostate tissue and for our specific objectives. Investigators must be aware that they will need to tailor the following protocol for their own research objectives
®尤其在皮肤组织的表皮分离和上皮层细胞培养中获得了广泛的应用。Dispase®I与Dispase®II两者的差别在于纯度的不同,Dispase®I经过滤除菌,且每mg Dispase®I的纯度和酶活远高于Dispase®II。 罗氏高纯度研究级别酶混合物Liberase Research Grade Enzyme Blends Liberase Research Grade Enzyme Blends包含了一系列酶混合物,它们由不同比例的中性蛋白酶(非梭菌蛋白酶)和高纯
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