- ￥211 - 1627
- abinscience
- France
- MW367022
- 2026年04月02日
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- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 英文名：
Recombinant Mouse TGFBR2 Protein, N-His
- 库存：
999
- 供应商：
abinscience
- 规格：
50ug/100ug/1mg
| 规格： | 50ug | 产品价格： | ￥211.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥311.0 |
| 规格： | 1mg | 产品价格： | ￥1627.0 |
| Product name | Recombinant Mouse TGFBR2 Protein, N-His |
|---|---|
| Catalog No. | MW367022 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | Q62312 |
| Protein length | Ile24-Glu166 |
| Nature | Recombinant |
| Predicted molecular weight | \ |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative Names | EC:2.7.11.30, TGF-beta receptor type II, TGF-beta receptor type-2, TGF-beta type II receptor, TGFR-2, TbetaR-II, Tgfbr2, Transforming growth factor-beta receptor type II |
| Species | Mus musculus (Mouse) |
| Note | For research use only. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验depends on product and its function. N-terminal sequencing revealed that the purified rBoNTC(Hc )-N is missing the first eight amino acids of the N-terminus of the protein, whereas the purified rBoNTC(Hc )-C protein is intact. After a mouse bioassay test
信息 1、Recombinant Gene Expression : Reviews and Protocols Editor(s): Paulina Balbás1, Argelia Lorence2 Affiliation(s): (1),Centro de Investigación en Biotecnología,CuernavacaMéxico (2)Virginia Polytechnic Institute,State University,BlacksburgVA
高压进展。机制上，BACH1是脯氨酸羟化酶PHD2的底物，缺氧减少PHD2介导的BACH1羟基化，削弱其与E3泛素连接酶VHL的结合，抑制泛素-蛋白酶体降解，增强BACH1蛋白稳定性；BACH1入核后直接结合TGFBR2启动子促进其转录，增强下游SMAD3信号及细胞外基质基因表达。Bach1缺失显著减轻小鼠肺动脉高压表型，TGFBR2抑制剂可缓解BACH1过表达的促病变作用。该研究揭示了BACH1作为肺动脉高压治疗的潜在新靶点。 推荐产品 靶点 重组蛋白 货号 BACH
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