- $495
- Leading Biology
- United States
- AMM04387G
- 2026年03月31日
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Mouse / IgG1
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 克隆性：
单克隆
- 库存：
100
- 宿主：
Mouse
- 规格：
7 ml
35kDa (non-reduced); 40kDa (reduced)
细胞定位：
Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:17081065}
形式：
Liquid. In PBS containing 0.02% sodium azide.
参考文献：
Kirsch AH et. al. Tissue Antigens. 1997 Aug;50(2):147-52
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD147 / EMMPRIN / Neurothelin antibody.
功能：
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
总结：
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
联系方式：
生物商城：http://www.annoron.com
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官方售后：400-965-8633
企业 QQ：3212874516、3198592576
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