- $495
- Leading Biology
- United States
- APR13232G
- 2026年03月31日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
156-185 aa
- 亚型：
Rabbit Ig
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 库存：
100
- 宿主：
Rabbit
- 靶点：
This SCYL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the N-terminal region of human SCYL1.
- 抗体名：
CVAK90, GKLP, NTKL, TAPK, TEIF, TRAP
- 规格：
100 μl
89631 Da
细胞定位：
Antigen Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner Isoform 2: Cytoplasm. Note=Cytoplasmic throughout the cell cycle Isoform 6: Nucleus
形式：
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献：
Tang, Z., et al., Biochem. Biophys. Res. Commun. 324(4):1324-1332 (2004). Kato, M., et al., Genomics 79(6):760-767 (2002). Liu, S.C., et al., Biochim. Biophys. Acta 1517(1):148-152 (2000). van Asseldonk, M., et al., Genomics 66(1):35-42 (2000).
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCYL1 antibody (N-term).
功能：
Regulates COPI-mediated retrograde traffic. Has no detectable kinase activity in vitro.
总结：
SCYL1 forms multimers following transfection into COS-7 cells. SCYL1 forms a 300-kD trimer using crosslinking reagents. Biochemical analysis revealed no phosphorylation or autophosphorylation activity.The 707-amino acid SCYL1 variant, variant 2, localized to centrosomes during mitosis. During interphase, fluorescence-tagged variant 2 localized in the cytoplasm as well as centrosomes. However, at the beginning of mitosis, the fluorescence appeared as a pair of bright nuclear foci that followed centrosome localization throughout mitosis, while maintaining diffuse cytoplasmic labeling. Endogenous variant 2 in HeLa cells showed a similar staining pattern. Centrosomal localization was independent of microtubules.
联系方式：
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