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- 详细信息
- 文献和实验
- 技术资料
- 库存:
10MG
- 保存条件:
室温
- 供应商:
西宝生物
- 英文名:
TELOMERASE INHIBITOR V
- 规格:
0.2mg
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文献和实验Screening of Telomerase Inhibitors
(G-quadruplex-interactive compound), BIBR1532 (non-nucleosidic reverse transcriptase inhibitor), 2′-O-methyl RNA, and peptide nucleic acids (PNAs; hTR antisense oligonucleotides). To determine minimal effective concentrations for telomerase inhibition
for cell lysis: 10 mM Tris-HCl, pH 7.4,50 mM NaCl, 5 mM EDTA, 50 mM NaF, 30 mM Na 4 P 2 O 7 ,and 1% (v/v) Triton-X100. 5. Protease inhibitors and phosphatase inhibitor are added fresheach time with the following final concentrations: 10 μg/mLaprotinin
Correlation of Telomerase Activity and Telomere Length to Chemosensitivity
of telomerase activity in cancer cells is rather universal, which suggests that telomerase inhibition as a novel and potentially selective target for therapeutic intervention. Although a telomerase-specific inhibitor has not been found yet, the possible effect
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