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- 技术资料
- 英文名：
RANKL [RANK Ligand; OPGL; ODF; TRANCE], extracellular
- 供应商：
西宝
- 库存：
大量
- 规格：
100 礚
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文献和实验Embryonic Stem Cells as a Model for Studying Osteoclast Lineage Development
are found tightly attached to bone matrix ( 1 , 2 ). Two cytokines, macrophage colony-stimulating factor (M-CSF) and receptor activator of NF-κB (RANK) ligand (RANKL; also known as OPGL, ODF, and TRANCE), are known to be responsible for this differentiation ( 5 –
TRAF‐Mediated TNFR‐Family Signaling
, such as TRANCE‐R and CD40, bind to TRAF6 and other TRAF proteins, activating various pathways including Src‐family kinases. IL‐1R and Toll‐like receptors are indirectly linked to TRAF6 through MyD88, Tollip, and IRAK.
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