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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
详见官方网站
- 亚型:
详见官方网站
- 形态:
冻干粉/浓缩液
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
详见说明书
- 适应物种:
详见说明书
- 宿主:
详见官方网站
- 应用范围:
详见官方网站
- 浓度:
1mg/ml
- 抗体英文名:
Granzyme B (granzyme 2 Cytotoxic T-lymphocyte-associated Serine Esterase 1) (GZMB) Rabbit anti-Human Polyclonal (N-Terminus) An
- 规格:
100ug,200ug,1mg
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文献和实验相关专题 T细胞被激活后,释放含穿孔素与颗粒酶的颗粒,在Ca2+的借助下,颗粒在靶细胞膜 上穿孔,进而颗粒酶(granzyme)进入靶细胞内,引起靶细胞DNA降解活动。对这种颗粒酶的研究也较多,已从人及鼠体内提取了10余种酶,认为起主要作用的是granzymea与granzymeB。 One mechanism used by cytotoxic T cells to kill tumor cells
Detection of Human and Mouse Granzyme B Activity in Cell Extracts
The serine protease granzyme B (GrB) is a key effector molecule in cell-mediated immunity, released by cytotoxic lymphocytes (CLs) to induce cell death in neoplastic or virus-infected cells. The ability to detect and measure GrB activity
CD8+ cytotoxic T lymphocyte (CTL) activity is currently believed to be one of the key immunologic mechanisms responsible for the prevention or attenuation of HIV-1 infection. The induction of CD8+ T cell activation may also result
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