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上海一基实业有限公司
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文献和实验In Vitro Assays for Induction of Drug Metabolism
and testosterone 6β-hydroxylase activities, respectively, whereas 7-benzyloxy-4-trifluoromethylcoumarin (BFC) O -debenzylase can be employed to assess both CYP1A and CYP2B form induction in rat hepatocytes. An assay for determining the protein content
The Use of NO Gas in Biological Systems
of NO may have complex biological reactivity. For example, dinitrogen trioxide (N2 O3 ) is a potent nitrosating agent that reacts with amines and thiols to generate N-nitroso and S-nitroso derivatives, respectively (6 –8 ). This problem has been addressed
Use of NO Donors in Biological Systems
that include organic nitrates [e.g., glyceryl trinitrate (GTN)], organic nitrites (e.g., iso amyl nitrite), inorganic nitroso compounds [e.g., sodium nitroprusside (SNP)], sydnonimines [e.g., molsidomine (SIN-1)], and S-nitrosothiols (RSNO) [e.g., S
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